49ers’ Brock Purdy, Trent Williams, Nick Bosa In Doubt For Week 12

The 49ers have run into steady injury trouble this season, and arguably their three most important players are in doubt for a Week 12 game against the Packers. Most notably, Brock Purdy has now gone through an MRI on his injured throwing shoulder.

Limited in practice over the past two days, Purdy is iffy for San Francisco’s Green Bay trip. John Lynch said during a KNBR interview (h/t Cam Inman of the San Jose Mercury News) the situation is “tenuous” and noted Brandon Allen would take the snaps in front of Joshua Dobbs if Purdy were unable to go.

Purdy has not missed a start since suffering a UCL tear in the 2022 NFC championship game, establishing himself as the 49ers’ full-time starter in that span. Meanwhile, the 49ers have seen neither Nick Bosa nor Trent Williams practice this week. Bosa is dealing with the oblique injury suffered against the Seahawks in Week 11, while Williams has played through an ankle issue.

Sounding alarm bells about the All-Pro left tackle’s situation, Kyle Shanahan said (via the San Francisco Chronicle’s Eric Branch) a pain-killing injection has not helped. Considering how the 49ers fared without Williams last season, this becomes a central concern for a team that has fallen to 5-5.

Williams took the pregame injection and played every offensive snap for the 49ers in Week 12, but the aftermath threatens to keep him out. Williams, 36, has not missed any time this season; his absences last year point to trouble if the 49ers do not have the future Hall of Famer available Sunday. The 49ers lost to the Bengals and Vikings without Williams, starting their second-half push when he and Deebo Samuel returned to action. Williams has been the NFL’s first-team All-Pro left tackle for the past three seasons, riding those accolades to secure a lucrative rework in August.

More to come.